The ISO 45 is one of the fastest-firing sub-machine guns in MW2, making it a powerful weapon to use. With these attachments, you will shred through those enemy players.

Released as part of MW2 Season 4, this SMG is already making waves, with many feeling it could be the new close-range meta.

If you want to utilize this weapon to its best capabilities and pick up a ton of kills, here is the best loadout for the ISO 45.

Best ISO 45 Loadout in MW2 – Attachments & Tuning

AttachmentTuningHow to Unlock
FTAC Castle Comp (Muzzle)+ 0.41 ↑
+0.23 →
556 Icarus Level 10
VLK LZR 7MW (Laser)– 0.18  ↓
-29.61 ←
STB 556 Level 5
EDGE 47 Grip (Underbarrel)+ 0.59 ↑
+0.30 →
M13B Level 16
Slimline Pro (Optic)– 1.35  ↓
+2.25 →
Lachmann Sub Level 11
45-Round Drum (Magazine)N/A ISO 45 Level 14
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ISO 45 MW2 Loadout

Best Secondary for ISO 45 in MW2

When wielding the ISO 45, the optimal choice for a secondary weapon would be a pair of dual-wielded pistols.

By equipping these pistols, you can significantly increase your kill potential in situations where they need to be swiftly deployed. Here are three recommended pistols that can greatly assist you in racking up kills:

  1. FTAC Siege
  2. X12
  3. P890

Best Perks & Equipment for MW2 ISO 45 Loadout

As a weapon that excels at being aggressive and quickly moving around the map, you will want to set your perks and equipment to suit this playstyle. These are our top suggestions:

  • Perk 1: Scavenger
  • Perk 2: Bomb Squad
  • Perk 3: Fast Hands
  • Perk 4: Quick Fix
  • Lethal: Drill Charge
  • Tactical: Stim

This ISO 45 build was made by Hero, a popular content creator known for his Modern Warfare 2 videos. You can watch the video for this loadout linked below:

Staff Writer
Scott is a passionate writer, who has now combined two of his favorite things - video games and journalism.